Nanofingers
Live long and prosper

Acknowledgment

Wenhao Shang

Jiangshan Wan

Abstract

Metabolism, cell apoptosis and immune system, all these physiological processes should be strictly regulated to sustain their homeostasis. The speed recovering to stable state directly determines the resistibility towards outer changes. To achieve this, here we build a device helping regulate a physiological process. We name it “Nanofingers”. It features like the Vulcan salute gesture, of which the two adjacent fingers can specifically capture a protein like a tweezer. With a special interaction mechanism, we can simultaneously regulate a physiological process from two aspects and remarkably enhance the regulation ability. In our case, we regulate thrombin and hirudin, two proteins with a contrary function in blood coagulation, trying to accelerate the blood coagulation when we are injured and in reverse prevent the formation of thrombus. The blood thus can maintain a stable state. “Live long and prosper”, the Nanofingers is a Vulcan salute from us towards the world.

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